To quickly get rid of fungal infections, it is necessary to use a reliable antifungal drug for topical therapy, such as Nizoral. Singapore is one of many countries in the world, in which this antifungal drug is sold and used.
Nizoral is an antimycotic from the azole group. Fungistatic and fungicidal effects of its active ingredient Ketoconazole lie in the inhibition of the synthesis of enzymes, which are an integral part of the cell membrane. Nizoral prevents the growth and reproduction of fungi, which leads to their death.
Nizoral has practically no systemic effect and is not absorbed into the bloodstream. After application to the skin, the duration of the antifungal action of Nizoral is about 1 hour. However, therapeutic drug concentrations in the upper layers of the epidermis persist 10-11 days after the last application.
Depending on the clinical indications, patients can use one of the two medicinal forms of Nizoral:
- Cream of 2% – to get rid of shingles, dermatophytes, etc.
- Shampoo of 20 mg/g – to get rid of dandruff, seborrheic dermatitis, etc.
The advantage for the patient is that Nizoral is sold in the best pharmacies of Singapore without a prescription.
Unlike other drugs that treat only the symptoms of skin fungal infections, Nizoral eliminates the cause of the disease: fungal parasites. Methods of Nizoral use depend on the pharmaceutical form:
- shampoo: once a day with a mandatory application of foam for 3-5 minutes before flushing;
- cream: apply 1-2 times a day on the area affected by a fungal infection.
Depending on the severity of the fungal infection and the susceptibility of the patient to the action of the antimycotic, the duration of antifungal therapy with Nizoral can vary from 3 days to 6 weeks.
For patients with dry type of seborrheic dermatitis, the optimal duration of Nizoral shampoo use is one month. After 30 days of regular use, you can switch to the use of Nizoral shampoo once every two weeks. To prevent the recurrence of seborrheic dermatitis, Nizoral shampoo can be used once a week.
How the gradual decrease in the symptoms of seborrheic dermatitis takes place with the regular use of Nizoral shampoo:
- in 1-2 weeks: oiliness of hair decreases;
- in 2-3 weeks: the secretion of sebum decreases;
- in 3-4 weeks: visible signs of the disease, like itching and flaky skin, dandruff, etc. disappear.
Seborrheic dermatitis can affect not only the scalp, but also the areas of the face and trunk. With a wide spread of fungal infection, you can combine periodic washing with shampoo and applying Nizoral cream 1-2 times a week for 30 days.
According to the International Conference on Mycology, conducted in Singapore, Nizoral was almost unanimously recognized by experts as the most effective means for topical therapy. The drug not only neutralizes fungi pathogens, but also removes all the symptoms, associated with fungal infections: itching, as well as redness, inflammation and flaky skin.
The advantages of topical therapy of fungal infections with Nizoral:
- exposure directly to the site of the disease onset;
- low probability of side effects with prolonged use;
- possibility of using high concentrations of the drug without the risk of systemic side effects;
- does not affect the course and pathogenesis of concomitant diseases, does not interact with drugs for systemic use.
Despite the fact that Nizoral is released in pharmacies without a doctor’s prescription, one of the obstacles to an effective antifungal therapy may be the high cost of the medication. To save money, patients can buy cheap Nizoral in one of the online pharmacies.
Nizoral belongs to the third generation of antifungal drugs and is the first trademark of Ketoconazole. The drug, synthesized more than 30 years ago, is a scientific development of the pharmaceutical company Janssen Cilag (later Johnson & Johnson). In 1982, the first case was documented of the positive effect of Nizoral on the pathogenesis of fungal infections.
The pharmaceutical company Johnson & Johnson obtained a marketing authorization for the sale of Nizoral cream in Singapore on May 13, 1988. Two years later, Nizoral shampoo appeared on the shelves of Singapore pharmacies.
Nizoral tablets were sold in Singapore in the past. However, in October 2013, the Health Sciences Authority (HSA) felt that the risks of using Nizoral for systemic use did not exceed the potential benefit and the drug was withdrawn from sale.
In the topical treatment of fungal infections, you can use not only Nizoral. In Singapore, you can find other Ketoconazole-based antimycotics. You can buy them under such trademarks, as: Nitozol, Antanazol, Pristine, Beatoconazole, Sebizole, Dezor, Formyco, Ninazol and Sunazol.
Singapore suppliers of Nizoral generics are such pharmaceutical companies, as Sunward, Pharmaforte, Zyfas, Apex Pharma, Beacons Pharmaceuticals, Dksh, Euro Asia Medico and Joyson.
According to the recommendations of the Dermatological Society of Singapore (DSS), Nizoral should be the drug of choice in the treatment of skin fungal infections. The drug firmly holds the top position among drugs for topical therapy of seborrheic dermatitis, shingles and other diseases. Without any significant financial investment by the Health Sciences Authority, sales of Nizoral continue to grow.