Diabetes is a growing problem in Singapore and other countries in Southeast Asia. Over the past 30 years, the number of Singaporeans with diabetes has increased by about 4 times. A sharp change in the statistics of morbidity is caused by negative changes in people’s lifestyle.
If diabetes has not been prevented at the pre-diabetes stage, try using Janumet. The Health Science Authority of Singapore approved this drug for the treatment of adult patients with type 2 diabetes.
Clinically tested Janumet has excellent advantages for improving health:
- Stable antihyperglycemic action.
- Reduction in the level of harmful cholesterol.
- Control or reduction in body weight.
- Reduction of the risks of diseases, associated with high glucose levels.
Janumet is a combined drug for the treatment of diabetes. It contains two active substances – Metformin and Sitagliptin. Both active ingredients possess antihyperglycemic effects. The action mechanism of the drug lies in:
- Increase in the absorption time of sugar in the gastrointestinal tract.
- Decrease in the postprandial and basal glucose concentration in blood plasma.
- Slowing of the rate of glucose production in the liver.
- Increase in the intensity of sugar absorption in muscles.
If you have been diagnosed with type 2 diabetes, buy Janumet in Singapore and start treating metabolic disorders as soon as possible. Depending on the endocrinologist’s recommendations, patient can use tablets:
- Immediate-release (IR) of 500mg/50mg, 850mg/50mg or 1000mg/50mg.
- Extended release (XR) of 500mg/50mg, 1000mg/50mg or 1000mg/100mg.
If you have not taken effective antihyperglycemic medications before, your endocrinologist will give recommendations on the use of Janumet. The treatment usually begins with the use of Janumet tablets with a minimum or medium dosage strength. The daily dose can be increased gradually.
- IR tablets are taken twice a day.
- XR tablets should be taken once every 24 hours.
It should be noted that Janumet should be taken in conjunction with changes in lifestyle. Patients should reduce their caloric intake and be physically active for at least 1 hour during the day.
Janumet is often prescribed as an antihyperglycemic first-line drug, especially for patients, who are overweight or obese. Prolonged use of Janumet does not lead to weight gain. Most patients, who take this drug, lose extra pounds. Weight reduction is the most important advantage of Janumet.
Several other drugs used to reduce blood sugar are available In Singapore, for example, Sulphonylurea or Insulin. If metabolic disorders are severe or poorly treatable, Janumet can be used in combination with Insulin or Sulphonylurea. During the combined anti-diabetes therapy, the recommended daily dose of Janumet decreases (as a rule).
The use of Janumet in combination with other antihyperglycemic agents may be more effective, than using only one drug. In addition, the administration of small doses of various anti-diabetic drugs reduces the risks of untoward medical occurrence.
Besides reducing the blood sugar level, Janumet can cause side effects. The consequences of a noxious response to Janumet are very different and range from mild discomfort to severe side effects (rarely).
The most common side effects of Janumet are related to the gastrointestinal tract. They include:
The list rarer adverse effects includes drowsiness, diarrhea, constipation, hives, arthralgia, upper abdominal pain, back pain or myalgia.
If you want to buy Janumet tablets in a Singapore pharmacy, you can ask the pharmacist about possible side effects and the reasons for their manifestation. It will be useful to learn how to reduce the intensity of adverse reactions.
The occurrence of undesirable effects depends on the individual sensitivity of the patient and the dose used. Most side effects disappear within the first few days of treatment, while the body adjusts to Janumet.
Do not consume large amounts of alcohol during the period of Janumet treatment. This is especially true, if the patient has insufficient or partially impaired liver function. The combination of alcohol and an antihyperglycemic drug can cause such symptoms, as fatigue, breathing problems, nausea and stomach pain.
The intake of Janumet during meals will reduce the risk of gastrointestinal side effects. A decrease in the daily dose will allow controlling other reactions.
Before Janumet appeared on sale, the Health Science Authority (HSA) examined the results of clinical trials of this drug. Premarket testing confirmed that the benefit of the anti-hyperglycemic action exceeds the potential risks of Janumet.
The Singapore HSA also monitors the safety throughout the marketed life of Janumet. If any adverse events have occurred, they can be reported to HSA.
It should be noted that Janumet is currently the only drug that contains Metformin and Sitagliptin, and is approved by the HSA. The immediate-release tablets were approved in April 2008, and the extended release tablets – in December 2014.
Today, no Janumet generics are available for sale in Singapore. Therefore, the price of this branded drug remains relatively high.
MSD Pharma is the only supplier of Janumet to Singapore. While the term of patent protection is valid, other pharmaceutical companies will not be able to supply Janumet generics.
If you want to reduce the cost of diabetes therapy, you can buy Janumet in Singapore online. In many online pharmacies, the price of Janumet tablets is lower than that in the usual pharmacies.
Online purchase of drugs to treat diabetes is a common practice throughout the world. Online pharmacies offer low prices, as well as:
- Ease and convenience of ordering.
- Timely delivery.
- Privacy and anonymity.
Janumet can be ordered in just a few minutes. Many online pharmacies work 24 hours a day. The purchase of this antihyperglycemic drug can be carried out at any time of the day, and not just during the day. After the order payment, Janumet will be quickly delivered to the specified address.