To optimize the therapy of anxiety disorders, patients should use a tranquilizer with a fundamentally new mechanism of action, like Xanax. The Singapore Psychiatric Association (SPA) recommends its patients to buy Xanax and use it in a standard scheme of mental illnesses treatment.
Xanax is a tranquilizer from the group of triazolo-benzodiazepines. The therapeutic effect of the active ingredient Alprazolam is based on the stimulation of benzodiazepine receptors in the brain. This group of receptors in turn is closely connected with GABA-receptors, which act as a brake mediator of external stimuli.
While the action of the antidepressants is aimed at eradicating depression and panic, tranquilizers eliminate the symptoms of psychological disorders – melancholy, anxiety, irritability and others. Thus, the anxiolytics eliminate the manifestations of the disease, and antidepressants eliminate its cause.
The uniqueness of Xanax lies in the fact that, being an anxiolytic, it exhibits antidepressant properties. The selective influence over GABA-receptors allows Xanax implement the antidepressant effect, which is absent in the spectrum of psychotropic activity of other anxiolytics.
According to experts of the Association for Psychiatric Rehabilitation Singapore (APRS), Xanax possesses other properties that distinguish it from other anxiolytics:
- average duration of action (4-6 hours);
- sedative effect and behavioral toxicity that are expressed to a smaller extent than in other drugs.
Xanax has no affinity for dopamine, serotonin, cholinergic, adrenergic, histamine and other receptors of the central and autonomic nervous system. Thus, Xanax is one of the most prominent representatives of anxiolytic drugs, which possesses a better tolerability with a clearer selectivity of action.
To get rid of depressive disorders, patients can use one of two Xanax dosage forms:
- tablets of 0.25 mg, 0.5 mg, 1 mg, and 2 mg
- sustained-release tablets of 0.5 mg, 1 mg, 2 mg and 3 mg
In pharmacy chains of Singapore, Xanax can only be obtained through a medical prescription, issued by a psychiatrist. Those, who did not undergo a medical examination, can be recommended to buy Xanax online without a prescription.
The dose of Xanax is selected individually for each patient and is adjusted during treatment depending on the severity of depressive and panic disorders and individual response to the drug action. People, who never took antidepressants, sedatives and hypnotics before, require lower doses of Xanax, than patients with an experience of stimulants use.
Before initiating therapy for anxiety and panic disorders, patients must undergo an examination with a hepatologist to make sure his liver is in an appropriate functional condition. Xanax clearance is lower, and the half-life is higher in patients with inflammatory and fibrotic changes in the liver, compared to healthy patients.
The dosage of conventional Xanax tablets is:
- for the treatment of depression: initial dose of 0.5 mg three times a day, maintaining daily dose of 1.5-4.5 mg in several intakes;
- for the treatment of panic disorders: 0.5-1 mg once before bedtime or 0.5 mg three times a day;
- for the treatment of anxiety disorders: initial dose of 0.25-0.5 mg 3-4 times a day, maintaining dose of 0.5-4 mg daily in several intakes.
The first signs of the mental state improvement are observed after a week of regular Xanax use. The Singapore Association for Mental Health (SAMH) recommends to use the anxiolytic for the treatment of mental disorders for 4-12 weeks. Already in the second week of Xanax use, the patient develops a long-lasting and stable anxiolytic effect without developing tolerance.
If a patient wants to take the medicine as rarely as possible, he should buy prolonged-release Xanax tablets. While conventional tablets should be taken 3-4 times a day, ER tablets – no more than 2 times a day.
At any stage of mental disorders treatment, patient can switch from one Xanax dosage form to another dosage form without fearing for his health. For example, the 0.5 mg dose of conventional tablets three times a day is equivalent to a 1.5 mg dose of ER tablets once daily.
Many patients with anxiety and panic disorders begin to consume alcohol to alleviate the symptoms of mental illness. However, if you buy Xanax and start using it to treat your mental disorders, you should completely stop consuming alcohol. The combination of Xanax with alcohol leads to a significant deterioration in the psychological state, as well as the appearance of aggression and irritability.
Xanax has not been proven effective in the anxiety disorders treatment that lasts more than 6 months and panic disorders treatment that lasts more than 8 months. When this period is not enough for the development of a stable therapeutic effect, further administration of Xanax is possible, but only under a careful dynamic observation.
To avoid the risk of drug dependence, it is recommended to phase out Xanax, and to avoid sharp cessation of therapy. At the Singapore Mental Health Conference (SMHC), it was noted that during the period of Xanax cancellation, which may last several weeks to months, the daily dosage of the drug is gradually reduced by 0.25-0.5 mg until complete withdrawal.
One of the obstacles to an effective therapy of anxiety disorders can be high drug costs in pharmacy networks. Patients with limited financial possibilities, however, can save money and buy cheap Xanax in one of the online pharmacies.
Xanax is the first trademark of Alprazolam. Synthesis and clinical studies of Alprazolam were carried out by the American company Upjohn. Xanax first appeared on the pharmaceutical market in the late 1980s.
The pharmaceutical company Pfizer obtained a marketing authorization for the sale of conventional Xanax tablets in Singapore on June 8, 1988. Almost a decade later – on January 24, 1997, prolonged-release Xanax tablets appeared on the shelves of Singaporean pharmacies.
Xanax is not the only drug that Singaporeans can use in the treatment of anxiety disorders. The medicine is also sold under the trademark Apo-Alpraz. The Singaporean provider of the anxiolytic is the pharmaceutical company Pharmaforte.